The answer is as nuanced as is the nickel position.
You want to utilize the players versatility and strengths as best you can without taking away, from the defense, or further enhancing the defense.
Like my team the Phins on how they would use Ramsey, a top flight CB. They would utilize him in nickel, in safety and the traditional outside CB.
I would like to add, I do wonder if they’ll have Snowden maybe blitz from his nickel spot this season. He’s quick and fast enough that it could be used as an occasional power tool. I remember Burgess being good at it, and thought Tao could be, before moving to safety last year.